Summary

The Bioinformatics Unit provides researchers at the CRG, CNAG-CRG, PRBB and external organizations with services of consultation, planning of NGS and other genomic experiments, NGS data processing, analysis and management, software and database development, bioinformatics training, and access to high-performance computing resources at the CRG. The Unit works in synergy with the Genomics Unit and the Biomolecular Screening & Protein Technologies Unit (BMS-PT) to support users through all steps of services that include high-throughput sequencing, from the planning of an experiment to delivery of timely and reliable results.

Projects & Services

  • Consultancy and training in bioinformatics methods and resources.
  • NGS experiment planning and budgeting.
  • Software development, evaluation and benchmarking.
  • Database development and management.
  • Genomics: structural variant detection; genome re-sequencing; de novo genome assembly; analysis of 5C and other high-throughput data; genome functional annotation.
  • Transcriptomics: analysis of data from RNA-seq, ChIP-seq, microarrays, and other high-throughput experiments; de novo transcriptome assembly; functional analysis of differentially expressed genes.
  • NEW services launched in 2015:
    • Metagenomics: Identification of microbial communities from WGS and 16S rRNA sequencing.
    • Analysis of structural variants from human exome and WGS data.
  • Large-scale projects in 2015:
    • ‘Saca La Lengua’ (Stick Out Your Tongue’): analysis of saliva microbiomes of Spanish school children, design of online competitions.
    • Analysis of structural variants from WGS data of a family trio.